Abstract
This systematic review and meta-analysis updates evidence pertaining to response inhibition in obsessive-compulsive disorder (OCD) as measured by the stop-signal task (SST). We conducted a meta-analysis of the literature to compare response inhibition in patients with OCD and healthy controls, metaregressions to determine relative influences of age and sex on response inhibition performance, and a risk of bias assessment for included studies using the Newcastle-Ottawa Scale (NOS). Stop-signal reaction time (SSRT), which estimates the latency of the stopping process deficit, was significantly longer in OCD samples than in controls, reflecting inferior inhibitory control (Raw mean difference = 23.43 ms; p = <.001; 95% CI [17.42, 29.45]). We did not observe differences in mean reaction time (MRT) in OCD compared with controls (Raw mean difference = 2.51 ms; p = .755; 95% CI [-13.27, 18.30]). Reaction time variability (RTSD) was reported in one study only. Age impacted effect size of SSRT, indicating inferior performance in older OCD patients than younger ones. We did not observe a significant effect of sex on SSRT or MRT scores. (PsycInfo Database Record (c) 2022 APA, all rights reserved).
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
