Observed differences in nutrition management at two time points spanning a decade in critically ill trauma patients with and without head injury

Abstract

BackgroundNutritional needs of trauma patients admitted to the intensive care unit may differ from general critically ill patients, but most current evidence is based on large clinical trials recruiting mixed populations. ObjectiveThe aim of the study was to investigate nutrition practices at two time points that span a decade in trauma patients with and without head injury. MethodsThis observational study recruited adult trauma patients receiving mechanical ventilation and artificial nutrition from a single-centre intensive care unit between February 2005 to December 2006 (cohort 1), and December 2018 to September 2020 (cohort 2). Patients were categorised into head injury and non–head injury subgroups. Data regarding energy and protein prescription and delivery were collected. Data are presented as median [interquartile range]. Wilcoxon rank-sum test assessed the differences between cohorts and subgroups, with a P value ≤ 0.05. The protocol was registered with the Australian and New Zealand Clinical Trials Registry (Trial ID: ACTRN12618001816246). ResultsCohort 1 included 109 patients, and 112 patients were included in cohort 2 (age: 46 ± 19 vs 50 ± 19 y; 80 vs 79% M). Overall, nutrition practice did not differ between head-injured and non–head-injured subgroups (all P > 0.05). Energy prescription and delivery decreased from time point one to time point two, regardless of subgroup (Prescription: 9824 [8820–10 581] vs 8318 [7694–9071] kJ; Delivery: 6138 [5130–7188] vs 4715 [3059–5996] kJ; all P < 0.05). Protein prescription did not change from time point one to time point two. Although protein delivery remained constant from time point one to time point two in the head injury group, protein delivery reduced in the non–head injury subgroup (70 [56–82] vs 45 [26–64] g/d, P < 0.05). ConclusionIn this single-centre study, energy prescription and delivery in critically ill trauma patients reduced from time point one to time point two. Protein prescription did not change, but protein delivery reduced from time point one to time point two in non–head injury patients. Reasons for these differing trajectories require exploration. Study registrationTrial registered at www.anzctr.org.au. Trial ID: ACTRN12618001816246.