Observe the clinical effect of acute attack of primary angle-closure glaucoma terated by laser peripheral iridoplasty

Abstract

Objective To evaluate the curative effect of laser peripheral iridoplasty as an initial treat-ment for acute attack of primary angle-closure glaucoma.Methods Non-randomized retrospective series of case studies.The acute attack of primary angle-closure glaucoma patients diagnosed with from July 2007 to July 2008 were divided into drug group and laser group according to whether used laser peripheral iridoplasty.Their clinical data were retrospective analyzed including the time of intraocular pressure decreased to 21mmHg(1 mmHg=0.133kPa), the amount used of mannitol.Results The time used to lower the IOP to 21 mmHg: drug group needed 5～24 hours,average 10.67 hours,while laser group needed 1～6 hours,average 3.08 hours. There was a statistical significant difference(t=4.359, P <0.05).The amount of mannitol used:drug group was 250 ～750 ml,average 437.5ml,while laser group was 125～375 ml,average 218 ml.There was a statistical sig-ificant difference(t =3.597, P <0.05).Conclusion Laser peripheral iridoplasty appears to be very quick, ef-fective and safe in treating acute attack of primary angle-closure glancoma patients.It can be applied as an initial treatment of it. Key words: Primary angle-closure glaucoma; Acute attack; Laser peripheral iridoplasty