Observations on the use of Furanace for the control of vibrio disease in marine flatfish

Abstract

Minimum inhibition concentrations (MICs) were determined for Furanace (Dainippon Pharmaceutical Co. Ltd.) against 17 strains of pathogenic vibrios isolated from marine fish and salmonidae. All the strains tested were sensitive to Furanace, the highest MIC being 3.1 μg/ml for one strain and the remainder being < 1.6 μg/ml. Plaice ( Pleuronectes platessa L.), Dover sole ( Solea solea (L.)) and brill ( Scophthalmus rhombus (L.)) rapidly took up Furanace from low-concentration baths (5–10 μg/ml) at 9.5–11.5°C. Uptake varied between species at these temperatures and in most cases blood levels above 1 μg/ml were achieved after 1 hour's exposure. Two hours after exposure over 70% of the Furanace had been eliminated from the blood.