Abstract

A study was made of the cardiac measurements, as ascertained roentgenographically, of 273 normal native Peruvian male residents of high altitudes. The data obtained were compared with the normal predicted values for white persons living near sea level. As judged by the transverse diameter and frontal area, the size of the cardiac silhouette was definitely greater in these people than in normal white inhabitants of low altitudes. The average increase in transverse diameter was 11.5 per cent, and, in frontal area, 163 per cent. In the age groups studied, no progressive enlargement with in creasing age was evident. The possible mechanism and significance of this “enlargement” are discussed. It is suggested that this may be one of a variety of adaptive changes which occur with prolonged exposure to low concentrations of oxygen.

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