Abstract
The influenza vaccines developed in the United States since 1940 have been inactivated virus vaccines given by subcutaneous, intradermal, or intramuscular injection. Protection of very high degree has been conferred on vaccinated persons, but no satisfactory solution of many of the problems involved in immunization against influenza has been found. Meanwhile, workers in Russia have concentrated their efforts on live vaccines, with use of attenuated virus strains administered by the respiratory route. Russian vaccines have not previously been tested in the United States. This report presents observations on the responses of 27 volunteers who received live vaccine in the fall of 1958. Material and Methods Vaccine.— The vaccine used in this study was prepared at the Metchnikov Institute in Moscow and was received through the good offices of the National Institutes of Health. It was a lyophilized suspension of the fourth allantoic passage of the Iksha (A 2 ) strain. When
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
