Abstract
s1 April 1963Observations on Albumin Metabolism in Nontropical Sprue and Effects of Human Serum Albumin or Gluten-restricted Diet Using Radioiodinated Human Serum Albumin and Metabolic Balance Studies.H. H. Scudamore, M.D., F.A.C.P., R. E. Sedlack, M.D., W. N. Tauxe, M.D., J. W. Rosevear, M.D., Ph.D.H. H. Scudamore, M.D., F.A.C.P.Search for more papers by this author, R. E. Sedlack, M.D.Search for more papers by this author, W. N. Tauxe, M.D.Search for more papers by this author, J. W. Rosevear, M.D., Ph.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-58-4-726_3 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe metabolism of albumin in patients having nontropical sprue has been evaluated by means of I131-labeled human serum albumin and compared with that of healthy subjects. Studies were made of metabolic nitrogen and calcium balance and of fat intake and excretion. The sprue in the 12 patients investigated ranged from mild to extremely severe with hypo-albuminemia, edema, and hypocalcemia. The immediate response to non-labeled human serum albumin administered intravenously in 4 patients and the long-term response to a gluten-restricted diet were measured.The intravenously administered I131-labeled human serum albumin had a shortened survival or half-time in the plasma owing to... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Rochester, Minn. (CS) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 April 1963Volume 58, Issue 4Page: 726-727KeywordsBlood plasmaCalciumDietEdemaExcretionFatsHypocalcemiaSerum albumin Issue Published: 1 April 1963 PDF DownloadLoading ...
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