Observational study of fluid administration in AKI and its relationship to outcome of the patients

Abstract

Background: The concept of acute renal failure (ARF) has undergone significant re-examination in recent years. Mounting evidence suggests that acute, relatively mild injury to the kidney or impairment of kidney function, manifest by changes in urine output and blood chemistries, portend serious clinical consequences . Acute kidney injury (AKI) is a common pathology In the intensive care unit (ICU) and postoperative setting[3] and is often associated with hemodynamic instability requiring fluid resuscitation with large volumes of fluid. Over the last 5 years there has been increased recognition that fluid accumulation is common in these patients and is exacerbated once AKI and oliguria develop . Objective: To determine the mean fluid balance and corelate with the outcome measured in terms of Mortality and morbidity among the patients with AKI. Materials and Methods: The present prospective observational study was done by the Department of Emergency Medicine at tertiary care hospital, from July 2016 to December 2016 among the patients admitted with the diagnosis of Acute kidney Injury. Based on the previous studies using the sample size formula a minimum sample of 50 was obtained and selected for the purpose of the study who met the inclusion criteria.