Abstract

Obesity is increasing globally generating serious non-communicable diseases. The antiobesity drugs in the market don’t have any impact on adipocytes; the root cause of obesity, but give rise to many side effects. Several clinical studies have shown the potential of Varanadi Kashaya (VK) mentioned in Ayurveda classic Ashtanga Hrudaya in suppressing adipogenesis and lipid accumulation favoring anti-obesity action without any side effects. Yet, the efficacy of VK in managing obesity in individuals with metabolic disorders has not been evaluated in detail. As the constituents of VK has hypocholesterolemic, anti-diabetic and antioxidant characteristics it can address metabolic disorders as well. This study aims to determine the efficacy of VK in an obese individual with metabolic disorders. Materials and Methods: VK was given for 30 days to an obese person with diabetes and hyperlipidemia and evaluated the changes in anthropometry, Ayurveda parameters and laboratory investigations. Results: High-risk apple shape body shifted into a ratio between apple and pear threshold; a moderate risk to health problems by reducing weight/hip ratio (0.95 to 0.84), LDL (112.6 mg/dl to 106.2 mg/dl), total cholesterol (180 mg/dl to 171 mg/dl) and Non-HDL levels (132 mg/dl to 129 mg/dl) Conclusion: VK has the potency to address both subcutaneous and visceral fat; reducing obesity and controlling obesity-related metabolic disorders.

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