Abstract
The directional prepondance of vestibulo-ocular reflex (VOR-DP) by the pendular rotation were observed on the pigmented guinea pig after the surgical obliteration of unilateral endolymphatic sac.•Four out of five guinea pigs revealed DP to the non-operated side and one revealed to the operated side after operation. Then three guinea pig changed DP from the non-operated side to the operated side 2-6 weeks later.•The progressing stage of the experimental endolymphatic hydrops in guinea pig considered to be a model of the pre-vertigo stage of Meniere's disease.
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