Observation on the efficacy of vitrectomy for dialysis patients with end stage renal disease

Abstract

Objective To observe the clinical efficacy of minimally invasive vitrectomy for dialysis patients with end stage renal disease(ESRD). Methods The clinical data of 21 eyes of 18 dialysis patients with ESRD, who underwent minimally invasive vitrectomy due to proliferative diabetic retinopathy or vitreous hemorrhage were retrospectively reviewed. Six eyes of 5 cases were treated with peritoneal dialysis and 15 eyes of 13 cases were received heparin-free hemodialysis. The visual acuity, intraocular pressure and complications intraoperative and postoperative were observed in two groups. Results The postoperative visual acuity improved in two groups(t=2.589, P=0.018). The difference of intraocular pressure was not statistically significant between before and after surgery (t=-0.476, P=0.639). The difference of visual acuity, intraocular pressure and the rate of intraoperative and postoperative complications were not statistically significant between two groups (P>0.05). Preoperative intravitreal ranibizumab injection had no influence on complications, surgery time and final visual acuity. Conclusion Minimally invasive vitrectomy can improve the final visual acuity and achieve retinal reattachment for dialysis patients with ESRD, who suffering from vitreous hemorrhage or proliferative diabetic retinopathy. Compared with peritoneal dialysis, heparin-free hemodilysis is unlikely to increase the risk of intra and postoperative complications. Key words: Renal disease, end stage, dialysis; Vitrectomy