Observation on the efficacy of aberration elimination program in femtosecond assisted laser in situ keratomileusis for the correction of myopia and myopic astigmatism

Abstract

Objective To observe the efficacy of aberration elimination program in femtosecond assisted situ keratomileusis (FS-LASIK)for the correction of myopia and myopic astigmatism. Methods A prospective study. From Dec. 2013 to Aug. 2014, 76 eyes of 76 cases with myopia and myopic astigmatism received aberration elimination program FS-LASIK .The right eye was the object of study.There were 37 eyes of low to moderate myopia and myopic astigmatism(<-6.0D) and 39 eyes of high myopia and myopic astigmatism(≥-6.0D). The Optikon 2000 corneal wavefront aberration analyzer was used to examine the corneal higher-order aberrations before and 3 months after surgery. The corneal higher-order aberrations included spab, coma and total higher-order aberrations. Results The difference of spherical aberration, coma and total higher- order aberrations were not statistically significant between before and 3 months after surgery(t=1.999, 1.508, 1.435; P=0.053, 0.080, 0.075). The difference of corneal higher-order aberration of patients with low to moderate myopia and myopic astigmatism were not statistically significant between before and 3 months after surgery(t=1.530, 1.774, 2.053; P=0.120, 0.080, 0.052). The difference of the corneal higher-order aberrations of patients with high myopia and myopic astigmatism between before and 3 months after surgery were statistically significant (t=3.408, 5.372, 2.829; P=0.005, 0.000, 0.005). The variational ratio and multiple of higher -order aberrations in low to moderate myopia and myopic astigmatism were less than that in high myopia and myopic astigmatism. Conclusion The aberration elimination program can effectively reduce the higher- order aberrations especially in low to moderate myopic astigmatism after FS-LASIK. Key words: Aberration, higher-order; Femtosecond assisted laser in situ keratomileusis; Program aberration elimination