Observation on the efficacy and labratory analysis of tear of two methods for extraction of corneal foreign body due to chestnut eye injury

Abstract

Objective To investigate the efficacy and laboratory analysis of tear of two different treatment methods: fibrin glue and mechanical extraction of cornea chestnut thorn. Methods The data of 48 eyes of 48 patients with corneal foreign bodies due to chestnut eye injury were enrolled and analyzed retrospectively. Patients were randomly divided into 2 groups: fibrine glue group of 24 cases and mechanical extraction group of 24 cases. The fibrin glue group was covered with fibrin glue on the corneal surface, and the mechanical extraction group received chestnut thorn extraction under the microscope. The treatment time and the labratory analysis of tear after surgery were compared between the two groups during the healing process. Results The time of extraction of corneal foreign body was (11.5±4.0) min in the mechanical extraction group and (3.5±2.0) min in the fibrin glue group, the difference was statistically significant (t=9.771, P=0.021). The healing time of corneal epithelium was (14.5±2.1) d in the mechanical extraction group and (5.7±1.1) d in the fibrin glue group. The difference between the two groups was statistically significant (t=19.142, P=0.037). The differnce in ocular surface index, Schirmer I test and tear measuring height were statistilally significant between the two groups(all P 0.05). Corneal matrix edema subsided 1 week after surgery in fibrin glue group and corneal epithelium was healed completely, but in mechanical extraction group it was not healed, and corneal matrix edema was obvious. Conclusion The fibrin glue for the treatment of corneal foreign body caused by chestnut eye injury can reduce the operation time, beneficial to corneal healing.It is a safe and effective method. Key words: Ocular trauma; Corneal foreign body, chestnut thorn; Fibrin glue; Mechanical extraction; Labratory analysis of tear