Abstract
Objective To observe the effect of Xiyanping injection combined with Jinhoujian spray in the treatment of children with hand-foot-mouth disease (HFMD).Methods 87 children with HFMD were randomly divided into two groups,45 cases in observation group and 42 cases in control group.Observation group was treated with Xiyanping injection intravenous dripping combined with Jinhoujian spray oral spraying,while control group was treated with Ribavirin injection intravenous dripping.The duration for treatment was 3-7 d.The treatment effect was observed in the following aspects:recovery of body temperature and oral pain,resumed oral intake,dissipated time of skin rash and mouth ulcer.Results The total effective rate of observation group was 91.11％ (41/45),higher than 73.81％ (31/42) of control group,with statistically significant difference (P ＜ 0.05).Recovery time of body temperature and oral pain,resumed oral intake time,dissipated time of skin rash and mouth ulcer of observation group were shorter than those of control group,with statistically significant differences (P ＜ 0.05).No obvious adverse reaction occunred in two groups.Conclusion Xiyanping injection combined with Jinhoujian spray in the treatment of children with hand-foot-mouth disease is effective,without obvious side effects. Key words: Hand-foot-mouth disease; Xiyanping; Jinhoujian; Children
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