Abstract
Objective To investigate the change of oxidative stress indicators and VEGF in aqueous humor and serum of patients with cataract.Methods One hundred and two patients (129 eyes) with cataract from April 2012 to June 2013 were selected as observation group,and included healthy volunteers 60 cases (120 eyes) in the same period as control group,then the levels of oxidative stress indicators (SOD,MDA,CAT,GSH-PX,LPO) and VEGF in aqueous humor and serum of two groups were compared,these indicators in aqueous humor of patients at different age intervals were also compared.Results The levels of MDA,CAT and VEGF in aqueous of observation group were higher than those indexes of control group,but the levels of SOD and GSH-PX were lower than those indexes of control group,all P ＜0.05.The levels of MDA,LPO and VEGF in serum of observation group were higher than those indexes of control group,but the levels of SOD were lower than those indexes of control group,all P ＜0.05.Increased with age,the levels of SOD and GSH-PX in aqueous of cataract patients were significantly decreased,and the levels of MDA and VEGF were significantly increased,all P ＜0.05.Conclusions The levels of oxidative stress indicators and VEGF in aqueous humor and serum of patients with cataract are different from normal population,and the level are related to the age. Key words: Cataract; Oxidative stress; VEGF
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
