Observation on health quality of life before and after the injection of antiangiogenic drug in vitreous cavity to patients with wet age-related macular degeneration

Abstract

Abstract Objective To explore the vision related health quality-of-life before and after the injection of antiangiogenic drug in vitreous cavity to patients with wet-AMD. Methods The 2000 edition of Visual Functioning Questionnaire-25 issued by National Eye Institute is applied, and the VRQL evaluation is conducted on the initial diagnosed patients with wet-AMD before and after the injection of ranibizumab drugs in vitreous cavity. Results Among the wet-AMD patients, patients with better distance visual acuity before the intravitreal injection get lower VFQ-25 score; while after the vitreous cavity injection, the VFQ-25 questionnaire score is related to the explanation and nursing of doctors and nurses towards patients, the better the nursing, the higher the score. Conclusion Before vitreous cavity injection, the degree of distance visual acuity is an important factor affecting VRQL of wet-AMD patients, in addition, the explanation and nursing of doctors and nurses toward patients during pre-operation, intra-operation and post-operation of intravitreal injection are also the import factors affecting VROL.