Observation of the application effect of central venous catheter in the chemotherapy of children with leukemia

Abstract

Objective To explore the application effect of peripherally inserted central catheter (PICC) chemotherapy in children with leukemia and its timing and nursing measures. Methods 84 children with leukemia treated by chemotherapy in our hospital were selected from April 2014 to January 2016, and divided into two groups according to the random number table method. 42 cases in the control group were treated by cephalic vein catheter before chemotherapy; 42 cases in the observation group were treated by basilic vein catheter, who were subdivided into the observation group A (21 cases, before chemotherapy) and the observation group B (21 cases, after 2 cycles’ chemotherapy) according to the timing of catheterization. The success rate of once catheterization, catheter blockage, puncture point bleeding, phlebitis of the control group and the observation group A were analyzed. The incidences of phlebitis of the observation group A, B were compared, and the clinical nursing countermeasures were explored. Results The success rate of once catheterization of the observation group A was 85.71%, higher than that of the control group (61.90%) (P 0.05). The incidence of phlebitis was lower in the three groups, without statistically significant difference (P>0.05). Conclusions The effect of chemotherapy with the central venous catheter before chemotherapy in children with leukemia is significant, which can effectively improve the success rate of once catheterization, reduce the rate of catheter blockage and the incidence of phlebitis. At the same time, we should pay attention to choosing the timing of catheterization, and give effective nursing measures to reduce the related complications, reduce the incidence of adverse events. Key words: Peripherally inserted central catheter; Leukemia; Chemotherapy; Phlebitis