OBSERVATION OF SERUM PARATHYROID HORMONE AND SERUM IONISED CALCIUM IN PATIENTS OF RENAL STONE

Abstract

Background: The life time prevalence of renal stone is estimated to be between 1 to 15 %. Symptomatic renal calculi pose a serious health problem to the patients and increase economic burden worldwide. The aim of the study is to observe the level of serum parathyroid hormone and serum ionised calcium in patients with renal stones. Methods: A total of 50 patients with the diagnosis of renal stone who came to MMCH, Madhubani, were evaluated for serum parathyroid hormone and serum ionised calcium level. Results: Serum parathyroid hormone was raised above the normal range in 2 out of 50 patients and serum calcium level was elevated in 12 patients, while phosphate, sodium, potassium, creatinine and blood urea were higher than the normal. Most of the urinary parameters were similar to other studies stating that they play an important role in renal stone formation. Conclusions: Although the pathogenesis of renal stone is multifactorial, metabolic factors do play an important role in their formation in both groups of population; first time stone formers as well as recurrent stone formers. Parathyroid hormone level, along with other metabolic factors like serum calcium, phosphate, uric acid and others should be assessed to know the exact pathology. Besides identifying anomalies, the evaluation also helps in determining the choice of treatment.