Observation of curative effect of oral particles medicine of spleen-strengthening and damp-removing concomitant with antiphlogistic and antipruritic lotion wet dressing in the treatment of eczema

Abstract

Objective To observe the curative effect of oral particles medicine of spleenstrengthening and damp-removing concomitant with antiphlogistic and antipruritic lotion wet dressing in the treatment of eczema.Methods 90 cases of eczema were randomly divided into treatment group and control group,45 cases in each group.Treatment group was given the treatment of self-made spleen-strengthening and damp-removing particles medicine,one dose a day,infused with warm water twice a day in the morning and night,and combined with antiphlogistic and antipruritic lotion:20 g powder soaked with 2000 ml warm water for 20 min,after cooling to room temperature,5-6 layers of gauze dipped in the liquid for a moment,when the gauze didn' t drip wetted the affected area about 20 minutes,2-3 times a day.Control group was given the treatment of topical mupirocin ointment combined mometasone furoate cream.The treatment lasted for 30 days.Observed scores of pruritus,rash form,rash area and total score in two groups before and after the treatment,at the same time compared the clinical efficacy and adverse reactions occurred during the treatment.Results After treatment,scores of rash form and rash area in treatment group were lower than those in control group,with statistically significant differences (P ＜ 0.05 or P ＜ 0.01); pruritus score in treatment group was higher than that in control group,with statistically significant difference (P ＜ 0.05); there was no statisticallysignificant difference in total score between two groups (P ＞ 0.05).The total effective rate in treatment group was 86.7％,while that in control group was 77.7％,without statistically significant difference (u =-1.590,P ＞ 0.05).There were 3 cases of skin burning sensation and pigmentation in treatment group,8 cases in control group.Conclusions Oral particles medicine of spleen-strengthening and damp-removing concomitant with antiphlogistic and antipruritic lotion wet dressing in the treatment of eczema had the same overall effect as the treatment of topical mupirocin ointment combined with mometasone furoate cream,but the former was better in improving patients' rash form and area with fewer adverse reactions,which could be an alternative in the clinical treatment of eczema. Key words: Eczema; Particles medicine of spleen-strengthening and damp-removing; Antiphlogistic and antipruritic lotion