Abstract
Porous Silk Fibroin Films(PSFFs) as dermis implant were used widely in biomaterials. To investigate angiogenesis in rat at different time after PSFFs implanting, CD34 was observed. Immunohistochemistry showed new blood vessels were mainly formed by sprouting next to PSFFs after 7 days operation. Microvessel Density (MVD) in PSFFs was 0, 3.54, 11.6, 24.5 after 1day, 7days, 15 days and 25days implantation respectively.
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