Observable Variations in Serum Toll Like Receptors (TLR4) as an Adjunct for Detection of Asymptomatic Neisseria Gonorrhoea Infection Amongst Sexually Active Women in Osun State, Nigeria

Abstract

The genus Neisseria contains commensal and pathogenic species that colonize human mucosal epithelia. The pathogenic species Neisseria gonorrhoeae and Neisseria meningitidis can induce inflammation and breach mucosal barriers. they have evolved mechanisms to promote growth and persistence in the host. In addition to living freely in the extracellular space, N. gonorrhoeae can invade the cytoplasm of host phagocytes, thereby evading detection and elimination by the innate immune system.