Abstract

The extraordinary life of Tipu Aziz is described through anecdotes told to his former residents and fellows. A giant of functional neurosurgery, his primate experiments first demonstrated the subthalamic nucleus and pedunculopontine nucleus as targets for surgery for Parkinson's disease and he pioneered deep brain stimulation for pain including of the anterior cingulate cortex. Despite various career cul-de-sacs he climbed the ziggurat to the pinnacles of British neurosurgery and neuroscience. A pinball wizard of functional neurosurgery, he was mentored by a bygone Madmen era of gentlemen: chain-smoking, heavy-drinking workaholics whose nonchalant bravado, ‘can-do’ attitude, love of mischief, merriment and well-placed profanity he exemplified. Sometimes sharing a cigarette with a patient before surgery, we will not see his like again.

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