Obez çocuklarda D vitamini düzeyleri: İnsülin düzeyi ve dislipidemi ile ilişkisinin değerlendirilmesi

Abstract

Obesity and vitamin D deficiency are both important important healthcare problems in childhood. The purpose of this study was to evaluate the association between body mass index, vitamin D status, insulin and triglyceride levels. 83 pediatric patients who were followed up for obesity in the Pediatric Metabolism Outpatient Clinic and received only healthy nutritional support were included in the project. Demographic data was obtained, height-weight measurements were performed and body mass index and percentile values were calculated. Serum 25 hydroxy-vitamin D, insulin, hemoglobin A1C, cholesterol and triglyceride levels of the patients were evaluated. The mean age of the pediatric patients included in the study was 10.73 ± 3.32 years. It was found that in 42.6% of the patients 25 hydroxy-vitamin D levels were below 10 ng / mL and in 47.1% of them vitamin D levels were between 20-30 ng/mL. Twelve % (n = 10) of the pediatric patients were evaluated as overweight and 88 % (n = 73) were obese. There was no statistically significant difference in serum 25 hydroxy-vitamin D, insulin, hemoglobin A1C, cholesterol and triglyceride levels between these two groups. On the other hand, negative correlations were found between body weight and 25 hydroxy-vitamin D levels and between body weight and insulin and triglyceride levels. Similar to this, a negative correlation was seen between 25 hydroxy-vitamin D and insulin levels and 25 hydroxy-vitamin D and triglyceride levels. This study reveals the relationship between body mass index values and vitamin D status of children in our region; vitamin D levels were inadequate in obese children and vitamin D levels decreased with increasing body weight. In addition, a negative correlation was found between vitamin D and insulin and triglyceride levels.