Abstract

Investigation of the following problems might yield information regarding the production of obesity: Two men of equal weight and height receive the same food and do the same amount of work for a similar period. One gains weight rapidly, the other does not. How is this explained? A decrease in basal metabolism has been observed in prolonged inanition or weight loss. Does a corresponding increase occur during periods of overfeeding? If so, is the increment similar in the two types of individuals mentioned? Is the stimulation of metabolism by protein, the so-called specific dynamic action, the same in the constitutionally obese as in normal individuals? Is work performed with less energy expenditure by the adipose than by the lean person? Students agree that there is no inherent change in basal metabolism except in the subthyroid group. SPECIFIC DYNAMIC ACTION OF PROTEIN IN OBESITY In 1900, Jacquet and Svenson 1 examined

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