Abstract
The prevalence of overweight in children and adolescents with attention-deficit/hyperactivity was determined by cross-sectional analysis of 62,887 children aged 5 to 17 years from the 2003-2004 National Survey of Children’s Health, in a study at Brown Medical School, Providence, RI.
Highlights
GEFS+ is inherited as an autosomal dominant trait with incomplete penetrance, and is characterized by the association of febrile and afebrile seizures
The above novel locus, the 6th to be identified for GEFS+, is located on chromosome 8p23-p21
The prevalence of overweight in children and adolescents with attentiondeficit/hyperactivity was determined by cross-sectional analysis of 62,887 children aged 5 to 17 years from the 2003-2004 National Survey of Children's Health, in a study at Brown Medical School, Providence, RI
Summary
GEFS+ is inherited as an autosomal dominant trait with incomplete penetrance, and is characterized by the association of febrile and afebrile seizures. GEFS+ is genetically heterogeneous, and has been linked to chromosome 2q21 (SCN1A), 19ql3 (SCN1B), and 5q34 (GABRG2). Links to 2p24 and 21q22 are more recent reports. The above novel locus, the 6th to be identified for GEFS+, is located on chromosome 8p23-p21.
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