Obesity complicated with insulin resistance treated with the electroacupuncture at the combination of back-shu and front-mu points电针俞募配穴治疗胕胖合并胰岛素抵抗的临床观察

Abstract

ObjectiveTo observe the influences of electroacupuncture at the combination of back-shu and front-mu points on insulin sensitivity indicators and somatological parameter indicators in the patients with obesity complicated with insulin resistance. MethodsA total of 60 patients with obesity and insulin resistance were randomized into a control group (30 cases, 4 cases of them dropped out) and a trial group (30 cases, 2 cases of them dropped out). In the control group, the intervention with diet and exercise were provided. In the trial group, on the base of the treatment as the control group, electroacupuncture was added at the combination of back-shu points and front-mu points, 3 times weekly. The duration of treatment was 12 weeks in two groups. The therapeutic effect and the somatological parameter indicators (body mass [BW], body mass index [BMI], waist circumference [WC], waist-to-hip ratio [WHR]) as well as the insulin sensitivity indicators (fasting plasma glucose [FPG], fasting insulin [FIN], insulin sensitivity index [ISI] and insulin resistance index [HOMA-IR]) before and after treatment were compared between two groups. Results① The effective rate was 92.86% in the trial group and was 57.69% in the control group. The effective rate of the trial group was higher than the control group, indicating the statistical difference (P < 0.01). ② BW, BMI, WC and WHR after treatment were all reduced obviously as compared with before treatment in two groups (all P < 0.01). After treatment, BMI, WC and WHR in the trial group were all lower than those in the control group (all P < 0.05) and the differences in BW, BMI, WC and WHR before and after treatment in the trial group were larger than those in the control group (all P < 0.01). ③ After treatment, FIN and HOMA-IR were all lower significantly than those before treatment in two group and ISI was increased significantly as compared with before treatment (all P < 0.01). After treatment, FPG was reduced significantly as compared with before treatment in the trial group (P < 0.01) and the difference in FPG was not significant statistically in the control group (P > 0.05). After treatment, FPG and HOMA-IR in the trial group were lower than the control group and ISI was higher than the control group (all P < 0.05). Besides, the differences in FPG, FIN, ISI and HOMA-IR before and after treatment in the trial group were larger significantly than those in the control group (P < 0.01, P < 0.05). ConclusionElectroacupuncture at the combination of back-shu and front-mu points in association with the intervention with diet and exercise is effective on obesity complicated with insulin resistance. The effects of this combined therapy are superior as compared with simple intervention with diet and exercise in body mass, body mass index, waist circumference and waist-to-lip ratio as well as fasting blood glucose, fasting insulin, insulin sensitivity index and insulin resistance index in patients.