Abstract

COVID-19, caused by the new coronavirus (SARS-CoV-2), reaches pandemic levels and can generate manifestations through asymptomatic processes until severe acute respiratory infection. In this scenario, the disorders associated with overweight and morbidities in patients with COVID-19 need to be clarified. The most evident complications include a restrictive respiratory pattern, but excess abdominal fat may accentuate the ventilatory deficit. The purpose of this article is to present the effects of adiposity and comorbidities in individuals affected by COVID-19, as well as to identify the possible mechanisms involved in the severe course of viral infection. The topics addressed reiterate the role of obesity in COVID-19, since it is considered a risk factor for morbidities such as type 2 diabetes mellitus, cardiovascular and liver diseases, which may aggravate the involvement of the respiratory tract. In this context, the obtaining of anthropometric and metabolic data is crucial to estimate the risk of complications to COVID-19. Several strategies for the treatment of the obese individual, including changes in lifestyle, may generate remarkable impacts on adipose tissue, contributing to a better prognosis in the face of the COVID-19 pandemic.

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