Abstract
AND OBJECTIVE: Obesity is an independent risk factor for chronic disease. The prevalence of obesity is especially high among Mexican American children. Peripheral blood monocytes are altered with obesity contributing to elevated systemic inflammation and increased risk of chronic disease. In addition, obesity alters the circu- lating levels of cytokines/chemokines that influence monocyte behavior. The study objective was to investigate alterations in blood monocytes and plasma cytokines/chemokine levels among healthy weight (standardized BMI (zBMI) #85th percentile; n = 66), overweight (zBMI 85th-95th percentile; n = 23), and obese (zBMI $95th percentile; n =3 9) Mexican American children.
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