Abstract
Chest wall toxicity (CWT), comprising chest wall (CW) pain and radiation-induced rib fracture, is a common adverse effect of lung stereotactic ablative radiotherapy (SABR) for treatments near the CW. However, there is currently no clear consensus on dosimetric constraints or fractionation schemes (single versus multiple) to mitigate this toxicity. The goal of this analysis is to identify predictive dosimetric parameters for CWT and to compare outcomes for patients undergoing single- vs. multi-fraction SABR.
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