Abstract
Immunosenescence can reduce the immune system’s ability to destroy cancer cells and effectively respond to pathogens, thereby increasing susceptibility to cancer development and proliferation. Previous studies have shown that T cell senescence might be one of the important features of immunosenescence mechanism, but lack of single cell evidences. This study aimed to investigate the associations between immunosenescence cells and treatment responses of Lung squamous cell cancer (LUSC) patients who received neoadjuvant immunotherapy.
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