Abstract

After excluding a lepidic component, primary lung non-mucinous adenocarcinomas will fall into the same pathologic stages (p-stages) as pure invasive tumors with the same invasive size according to recommendations by the Eighth edition of the TNM staging system. The favorable survival for part lepidic tumors has raised the question whether they should be staged differently from purely invasive tumors lacking a lepidic component. We sought to investigate whether the presence or proportion of the lepidic component is associated with patient outcomes within the same p-stage according to invasive size.

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