Abstract

Purpose The IAEA protocol (TRS-398) for absorbed dose to water measurements in therapeutic MV photon beams, recommends that ionization chambers be calibrated directly in MV accelerator photon beams rather than in cobalt-60 combined with generic beam quality correction factors ( k Q ) tabulated in the protocol. The purpose of this work was to study the feasibility for secondary standards laboratories to provide direct MV calibrations for hospitals and to evaluate the benefit of such calibrations versus conventional cobalt calibrations. Methods A laboratory with the potential to provide direct MV calibrations was established. It includes both a cobalt irradiator and a linear accelerator with the following MV beams: 4, 6, 10, 15, and 18 MV with flattening filter and 6 and 10 MV without flattening filter. Procedures were designed for accurate positioning of ionization chambers, beam output monitoring and relevant ionization chamber correction factors. Over a two-month period, k Q -factors were measured in all beams for seven nominally identical chambers (IBA FC65G) covering a wide range of serial numbers. Traceability to primary standards were established using transfer chambers. The results were compared with published k Q -factors from TRS-398. Results The monitoring of beam output using an external monitor chamber was found to be essential for calibration purposes: The raw accelerator output changed systematically by 0.4% over the measurement period. However, with an external monitor chamber, the output variability was reduced to less than 0.05% (1 sd). For each beam quality, the relative standard deviation for the measured k Q factors for the seven ionization chambers was about 0.07%. Conclusions The study demonstrates the feasibility of highly reproducible MV calibrations at the level of a secondary standards laboratory, and the closeness of agreement (sd k Q -factors may be adequate for the tested ionization chamber model. Ongoing work focuses on characterization of additional ionization chambers models (PTW30013, PTW31021, and NE2571) and on an improved estimation of the uncertainty related to establishing traceability to primary standards. The latter work includes direct use of water calorimetry in the specific accelerator beams of the laboratory.

Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call