Abstract

The optimal treatment strategy for T4 NSCLC that presents as a primary tumor with additional pulmonary nodules in an ipsilateral lobe is not well characterized. While current National Comprehensive Cancer Network (NCCN) guidelines suggest surgical resection for N0 or N1 disease, the recommended treatment for N2 disease is chemoradiation therapy without surgery. Few studies with limited sample sizes, however, have assessed the use of surgery for patients with T4, N2 (Stage IIIB) NSCLC. This study evaluated long-term survival of patients with T4, N2 NSCLC who received multimodal therapy including surgery as compared with patients who received chemoradiation alone.

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