Abstract
Ramucirumab (RAM) plus FOLFIRI has been considered as 2nd-line treatment standard of care for RAS wild-type metastatic colorectal cancer (mCRC) after anti-EGFR antibody containing chemotherapy. However, there have been few studies which prospectively evaluated the efficacy and safety of RAM plus FOLFIRI after anti-EGFR antibody therapy in mCRC. We therefore investigated the efficacy and safety of RAM plus FOLFIRI as 2nd-line treatment in patients with RAS wild-type mCRC previously treated with anti-EGFR antibody containing chemotherapy.
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