O44-4 - A Simple Non-invasive Method of Estimating Pulmonary Vascular Resistance by Doppler Echocardiography in Patients without Acute Exacerbated Left Heart Failure

Abstract

Background: Assessment of pulmonary vascular resistance (PVR) plays an important role in managing patients with elevated pulmonary artery pressure. To date, several formulae for estimating PVR with echocardiography have been proposed. The problem is, however, most of them contain values not always measured in routine echocardiographic examination, which makes it difficult to assess one's PVR retrospectively. The aim of this study is to investigate feasibility of a new simple echocardiographic measurement of PVR (PVRecho), peak tricuspid regurgitation pressure gradient divided by three times of left ventricular cardiac output derived from Doppler echocardiography (TRPG/3LVCO), in patients without acute exacerbated left-sided heart failure. Method: From July 2014 to May 2017, PVR calculated by right heart catheterization (PVRcath), and TRPG and LVCO by echocardiography were available in 57 patients. Patients with cardiac shunt, atrial fibrillation, severe mitral regurgitation, or emergency catheterization were excluded. Among these patients, PVRecho and PVRcath were compared using linear progression and Bland-Altman analysis. Result: Mean PVRcath was 2.2 ± 1.8 WU. PVRecho had a good correlation with PVRcath (r = 0.66, P < .001). On Bland-Altman analysis, the mean difference was 0.1 ± 1.3WU, which is comparable with other formulae previously reported. Patients with lower pulmonary capillary wedge pressure showed better correlation between PVRecho and PVRcath. Conclusion: The new simple formula for estimation of PVR showed comparable correlation with previously reported formulae.