Abstract

Purpose of the study Despite recent advances in the reduction of morbidity and mortality after the advent of HAART, a large number of HIV patients still present late with advanced immunodeficiency. In these patients the risk of developing AIDSdefining events (ADE) may depend on a solid immune reconstitution with immune-discordant responses being at higher risk. We aimed to determine risk factors for the development of ADE in patients who begin fully suppressive antiretroviral treatment with CD4 counts <200 cells/ μl.

Highlights

  • O423 Risk of new AIDS-defining events in patients with advanced immunodeficiency during suppressive HAART: results from the German ClinSurv cohort

  • Abstracts of the Ninth International Congress on Drug Therapy in HIV Infection Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/pdf/1758-2652-11-S1-info.pdf

  • Despite recent advances in the reduction of morbidity and mortality after the advent of HAART, a large number of HIV patients still present late with advanced immunodeficiency. In these patients the risk of developing AIDSdefining events (ADE) may depend on a solid immune reconstitution with immune-discordant responses being at higher risk

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Summary

Introduction

O423 Risk of new AIDS-defining events in patients with advanced immunodeficiency during suppressive HAART: results from the German ClinSurv cohort. Despite recent advances in the reduction of morbidity and mortality after the advent of HAART, a large number of HIV patients still present late with advanced immunodeficiency. In these patients the risk of developing AIDSdefining events (ADE) may depend on a solid immune reconstitution with immune-discordant responses being at higher risk. We aimed to determine risk factors for the development of ADE in patients who begin fully suppressive antiretroviral treatment with CD4 counts

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