O26 Effectiveness of laser photobiomodulation of InGaAlP on wound healing and GaAlAs laser on the blood sugar amount in diabetic rats

Abstract

Material and Methods: By light, scanning and transmission electron microscopy methods and morphometry, structural changes of the organs of patients (P) in pathology and changes in the correlation of PFE in peripheral blood were studied in such lesions as: psoriasis (30 P), lichen ruber planus (32 P), eczema (36 P), neurodermatitis (34 P), periodontitis (42 P) and bleeding, encephalopathy in liver cirrhosis (24P). ILIB and PLIB were conducted every other day, duration 30min (10 12 treatments) using the apparatus “Matrix-VLOK”, radiating head KL-VLOK a special needle with a teflon coating, the wavelength 0.63 microns, the power output of the optical fiber 1.5 2 mW. PLIB and local irradiation of pathological foci was performed using the apparatus “Mustang 017-MCS-PC”, with a magnetic attachment, which creates the magnetic field 50 MLT. Laser therapy was carried out with exposure by 5 min, frequency 1000Hz, 15 16 treatments. Results: Shift of varying degree in the ratio of the D and PFE occurred in all studied types of pathology. Portion of D decrease from 1.2 till 2 times. It is depends from form of pathology. This is accompanied by corresponding specific changes of structures in the foci of affected organs. It is characteristic, that the percentage of PFE is higher in 1.5 2 time in the blood obtained from lesions, than in peripheral blood of the same patients, affected by skin disease and periodontitis. Isolated local laser irradiation and the isolated use of ILIB and PLIB cause pronounced reduction of changes in organ and normalization of red blood cells. The most pronounced effects of normalization occur at the integrated use of blood irradiation together with local irradiation of pathological lesions. Among the methods of irradiation of blood, most efficient ILIB was at a wavelength of 0.63 microns. Local irradiation of foci of pathological changes, not only leads to reduction of specific alterations of the structure, but also to the marked normalization of the ratio: D PFE. This is especially pronounced in case of laser therapy of periodontitis. Integrated laser therapy causes normalization of erythrocytes’ forms in the lumina of microvessels and a reduction of intravascular microthrombi, which leads to normalization of microcirculation. Conclusion: The local laser influence and laser irradiation of blood leads to a reduction of changes in the lesion focus and normalization of relations of D and PFE. The most effective is integrated local irradiation of pathological lesions with ILIB.