O100 / #804 THE LINK BETWEEN SPINAL CORD STIMULATION FOR PAIN AND THE PARASYMPATHETIC NERVOUS SYSTEM: IS THERE AN INFLUENCE ON THE AUTONOMIC NERVOUS SYSTEM?: TRACK 1: MECHANISMS OF ACTION, MAPPING AND SPINAL CORD STIMULATION

Abstract

Despite the well-known clinical effects of spinal cord stimulation (SCS), the mechanisms of action have not yet been fully unraveled. It is hypothesized that SCS is able to influence the autonomic nervous system. In patients with chronic pain, a relative lower parasympathetic activity is already suggested based on heart rate variability measurements. The aim of this study is to further explore the influence of SCS on the autonomic nervous system in patients with Persistent Spinal Pain Syndrome Type 2 (PSPS T2) by evaluating whether SCS is able to influence (electrochemical) skin conductance, blood volume pulse, heart rate, and respiration rate.