Abstract

of life (-.282 -.105; p <0.01) and with the risk of suicide (r: -.36; p: < .05). Particularly, subjects with suicide ideation showed higher scores on the level of depression, (t= -4.823; p: 001) hopelessness, (t= -4.261; p: 001) and emotional abuse (t= -3.526; p: 001). Conclusions Our data confirm that patients with MOH showed an anxiety-related temperament associated with high levels of depression, hopelessness and suicide risk. Suicide attempts seem to be more frequent in patients suffering from migraine than in the general population, especially in females. Suicidal ideation was associated with higher headache frequency and headache-related disability. The evidence of a possible link between chronic headache and psychiatric disorder is not a recent finding. Back in 1895, the occurring depressive mood, irritability, and anxiety in these patients [4] was described. Our findings indicate that patients with a diagnosis of MOH and migraine have severe hopelessness, and suicide risk. This evidence suggests that psychologic assessment is necessary in patients with MOH, and also that the presence of headache has to be carefully monitored in patients with mental illness. Written informed consent to publication was obtained from the patient(s).

Highlights

  • Migraine is one of the major causes of disability and lost working days worldwide [1]

  • The results showed that females present higher levels of anxiety (t= 3.392; p: < 001)

  • Our data confirm that patients with Medication-overuse headache (MOH) showed an anxiety-related temperament associated with high levels of depression, hopelessness and suicide risk

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Summary

Introduction

Migraine is one of the major causes of disability and lost working days worldwide [1]. Medication-overuse headache (MOH) is one of the most common forms of chronic daily headache (CDH) [2], with a prevalence in the adult general population of 1%-2% [3]. MOH is often comorbid with emotional disturbances and disordered personality traits. The aim of the present study was to explore the impact of mental illness among patients with migraine. Hopelessness, suicide risk and quality of life were associated with temperament and trauma in MOH patients

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