Abstract
Background The habituation phenomenon is a frequency-dependent form of non-associative learning which reflects the excitability level of both sensory and pain systems. We previously demonstrated a frequency-dependent deficit of habituation of the conventional blink reflex in cluster headache (CH) [1]. We investigated the habituation of the trigeminal nociceptive system by studying the habituation of the late component (R2) of the nociceptive blink reflex (nBR) in a wide range of stimulation frequencies in CH and paroxysmal hemicrania (PH).
Highlights
The habituation phenomenon is a frequency-dependent form of non-associative learning which reflects the excitability level of both sensory and pain systems
We previously demonstrated a frequency-dependent deficit of habituation of the conventional blink reflex in cluster headache (CH) [1]
We investigated the habituation of the trigeminal nociceptive system by studying the habituation of the late component (R2) of the nociceptive blink reflex in a wide range of stimulation frequencies in CH and paroxysmal hemicrania (PH)
Summary
Frequency-dependent habituation deficit of the nociceptive blink reflex in cluster headache and paroxysmal hemicrania. Armando Perrotta1*, Maria Grazia Anastasio, Gianluca Coppola, Anna Ambrosini, Roberto De Icco, Giorgio Sandrini, Francesco Pierelli. From Abstracts from the 1st Joint ANIRCEF-SISC Congress Rome, Italy. From Abstracts from the 1st Joint ANIRCEF-SISC Congress Rome, Italy. 29-31 October 2015
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