Abstract

Objective markers of therapeutic deep brain stimulation (DBS) for Parkinson’s disease (PD) are needed to tailor stimulation on a patient-specific basis. Recent studies suggest that subthalamic nucleus DBS evoked resonant neural activity (ERNA) may be used to refine targeting and possibly identify therapeutic stimulation parameters [1]. However, ERNA has not been studied in the pallidum, and whether it could be used to guide intraoperative targeting or stimulation programming is unknown. We aimed to determine if ERNA is present with pallidal DBS and if pallidal ERNA features are correlated with baseline PD neurophysiology.

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