O-004 Endovascular therapy in large infarct core strokes: a subgroup analysis of the trevo registry

Abstract

Introduction The recent thrombectomy trials were largely limited to patients with small strokes on presentation. We evaluate the outcomes of thrombectomy in patients with large strokes on baseline imaging. Methods Patients were derived from a large prospective multicenter international stent-retriever registry (n=2,010). Baseline NCCT-ASPECTS and Infarct Core Volumes on CT perfusion (rCBF 50 mL if age Results A total of 1,193 patients were included in the ASPECTS analysis. As compared with patients with higher baseline ASPECTS, low baseline ASPECTS (0–4, n=78; 5, n=78) patients were generally younger, had higher stroke severity, and tend to have less comorbidities and undergo thrombectomy at later times (table 1a). TICI-3 reperfusion was higher in the higher-ASPECTS group but other reperfusion outcomes were similar. Safety was comparable. 90-day mRS 0–2 rates were significantly higher in the high-ASPECTS group (p Conclusion Patients with large baseline cores may still achieve favorable outcomes with endovascular treatment. Disclosures R. Nogueira: 2; C; Stryker Neurovascular. D. Liebskind: 2; C; Stryker Neurovascular. E. Veznedaroglu: 2; C; Stryker Neurovascular. R. Budzik: 2; C; Stryker Neurovascular. R. Gupta: 2; C; Stryker Neurovascular.