Abstract

A. S. Loevenhart, 1 in 1910, used o -iodoxybenzoic acid in the treatment of seven cases of arthritis in Cook County Hospital, Chicago. The use of this drug in arthritis was revived by Young in 1923, while at the University of Wisconsin, and continued by Young and Youmans 2 at the University of Michigan in 1924. Their results were reported at the Dallas session of the American Medical Association. In September, 1925, Dr. A. G. Young of the Department of Pharmacology in the University of Michigan Medical School urged me to study the action of the drug in a series of cases in the Wisconsin General Hospital. Having received further advice as to procedure from Dr. A. S. Loevenhart of the Department of Pharmacology in the University of Wisconsin Medical School, I began using the drug on our first patients in October, 1925. In addition to the twenty-one cases treated

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