Abstract
Introduction: Airway management guidelines recommend the preoxygenation of obstetric patients to an end-tidal oxygen (etO2) concentration of 90% or more prior to general anaesthesia. A previous study showed that despite a plausible role for high-flow humidified nasal oxygen (HFNO) in this context, only 60% of participants achieved this target after t hree minutes of HFNO. [1] Tan PCF, Millay OJ, Leeton L, Dennis AT. High-flow humidified nasal preoxygenation in pregnant women: a prospective observational study. Br J Anaesth 2019;122:86-91. Google Scholar This was vastly lower than reported rates with face mask (FM) oxygen. We conducted a randomised controlled crossover trial to determine if HFNO is non-inferior to FM oxygen for increasing etO2 concentration after simulated preoxygenation of women in late pregnancy (gestational age ⩾ 36 weeks).
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