Abstract
Previously published results of sperm analysis using multicolor FISH in XXY indicated the presence, in most cases, of an increase in the proportion of abnormal XY and XX spermatozoa in XXY males. It has been reported that the sex chromosome abnormality incidence rate for ICSI children increased when Klinefelter syndrome patient sperm had been used. We conducted this study to investigate the mechanism of germ-cell mosaics.
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