Abstract

Most Y chromosome microdeletions occur on the long arm (q) and these microdeletions were mapped to three no overlapping regions, named as azoospermic factor (AZF). Deletions involving the AZFc region account for up to 90% of all Yq deletions with phenotypes varying from azoospermia to severe oligospermia and occasionally, mild oligozoospermia. The AZFc region, mainly DAZ gene cluster was the most frequently deleted region. The aim of this study was to evaluate the prevalence and type of Y microdeletions (AZFb, AZFc-DAZ) in Korean with male factor infertility.

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