Abstract
Tumor Treating Fields (TTFields) are an anti-mitotic, regional treatment modality, utilizing low intensity alternating electric fields delivered non-invasively to the tumor using a portable medical device. TTFields are approved by the FDA for the treatment of glioblastoma and malignant pleural mesothelioma. In vitro and in vivo TTFields at 150 kHz reduced the proliferative potential of hepatocelluar carcinoma (HCC) cell lines. In patients with Barcelona clinic liver cancer (BCLC) stage C or stage B following failure of loco-regional treatments, systemic therapies are the standard of care in eligible patients.
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