Abstract
This study was aimed at evaluating the nutritional value of the mesocarp of Raphia hookeri (Rh) fruit and the effect of powder and aqueous extract of the fruit on hematological parameters in rats which have undergone neurotoxicity by aluminum chloride. The nutritional content was evaluated with the standard method. Seven groups of six Wistar rats were used, neurotoxicity was induced by 4.2 mg/kg of body weight of aluminum chloride 3 times a week intraperitonealy with treatment. Rat treatment was as follow: aqueous extract at 200 and 400 mg/kg body weight, 5 and 10% of formulation, negative, positive and normal groups. The experiment lasted 28 days. The data obtained from the nutritive value showed that Rh mesocarp is a good source of lipids (48.97%), fibers (25.82%), calcium (3183.3mg/100g of dry matter), potassium (1218.3 mg/100g of DM), zinc (0.88 mg/100g of DM) and selenium (8.6 mg/100g of DM). Nevertheless, it contains a little amount of phytic acid and hydrocyanic acid which is acceptable for human consumption. It can then be used in many formulations as a source of these nutrients. Aluminum administration indicates the reduction in food intake, a low weight gain and Hematological alteration in the Positive control group. However, consumption of Rh mesocarp indicated an increase in food intake, weight gain and a restoration of hematological parameters to the normal level with the best values in groups that were administered Rh powders (Rh5% and Rh10%). 
 
 Raphia hookeri mesocarp is a rich source of nutrients involved in the prevention of hematological disorder.
Highlights
Aluminum (Al) is a metal which is widely distributed in the environment
This study was aimed at evaluating the nutritional value of the mesocarp of Raphia hookeri (Rh) fruit and the effect of powder and aqueous extract of the fruit on hematological parameters in rats which have undergone neurotoxicity by aluminum chloride
The data obtained from the nutritive value showed that Rh mesocarp is a good source of lipids (48.97%), fibers (25.82%), calcium (3183.3mg/100g of dry matter), potassium (1218.3 mg/100g of DM), zinc (0.88 mg/100g of DM) and selenium (8.6 mg/100g of DM)
Summary
Aluminum (Al) is a metal which is widely distributed in the environment. It is found in the soil, water and air. This metal is extensively used in daily life as medicine, food additive, vaccines adjuvants, phosphate binders, dialysis, total parenteral nutrition solutions and foods, increasing exposure of human being to it (Newairy et al, 2009). Biological effects of aluminum (Al) are linked to the development of many diseases. Many studies have shown that AlCl3 induces toxic effects on the brain, bone, immune and hematopoietic system (Gu et al, 2009). A chronic exposure to aluminum diminishes affinity of transferrin for aluminum due to the fact that the binding sites of transferring available for aluminum are mostly occupied by iron. (Azadeh & Mohammad, 2011)
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