Nutritional status in kidney transplant patients before and 6-month after transplantation: Result of PNSI study.

Abstract

Kidney transplantation is an essential treatment in management of kidney failure patients. The present study evaluated and compared the nutritional status of renal transplant patients before and 6 months after kidney transplantation and in comparison with healthy individuals. A multi-center, case-control study was conducted among 40 kidney transplant recipients and 40 healthy adults. Biochemical tests, anthropometric indices, and dietary intake were collected at baseline and 6 months post-transplant and compared with healthy controls. Anthropometric indices of the participants increased in post-transplant period compared to baseline (p<0.05). The calories, fat, carbohydrates, and selenium intakes also increased in patients compared to before transplantation and healthy controls. The mean score of malnutrition index in patients, before transplantation were: good nutrition status (A)=42.5%, mild to moderate malnutrition (B)=52.5%, and severe malnutrition (C)=5%, that changed to A=75%, B=20%, and C=5% six months after surgery. The mean score of malnutrition index in pre-transplant patients were: A=42.5%, B=52.5% and, C=5%, which changed to A=75%, B=20% and C=5% after 6 months. Experimental results showed that mean plasma levels of albumin, total protein, calcium increased as well as mean plasma levels of magnesium and phosphorus decreased over six months (p<0.001). Kidney transplantation led to improvement in clinical and nutritional status of patients with renal failure. Improving dietary intakes as part of the medical care process can help improve their medical conditions.