Nutritional status and its related factors in patients undergoing allogenetic hematopoietic stem cell transplantation

Abstract

Objective We tried to investigate the nutritional status and related factors in patients undergoing allogenetic hematopoietic stem cell transplantation. Methods A total of 75 patients were re-cruited from a class-three hospital in Suzhou. They were investigated with a basic information questionnaire and the Patient-Generated-Subjective Global Assessment (PG-SGA). The related factors influencing nutri-tional status were analyzed. Results The PAB level began to rise since conditioning regimen, and it rose to the highest level in the second week, then began to decline. The weight and the BMI had been declining in the four weeks since conditioning regimen. 29.33% of the patients were malnourished, the scored PG-SGA was (5.60±4.96), the percentage of patients with dietary problems was 33.3% before conditioning regi-men; 85.33% of the patients were malnourished, the scored PG-SGA was (19.26±7.18), the percentage of patients with dietary problems was 93.2% in the second week since conditioning regimen; 85.33% of the patients were malnourished, the scored PG-SGA was (12.95±6.19), the percentage of patients with dietary problems was 75.8% in the fourth week; Age is the main factor affecting the patients' albumin level in the second week. Conclusions The nutritional status of patients deteriorated and the percentage of patients with malnutrition increased during allogeneic hematopoietic stem cell transplantation. Clinical staff should pay atten-tion to the assessment of nutritional status, and give a reasonable nutritional support when necessary. Key words: Allogeneic hematopoietic stem cell transplantation; Nutritional status; Nutritional as-sessment